Trial intelligence / Profile preview

NeoCOAST: Neoadjuvant Durvalumab Alone or with Novel Agents in Resectable Early-stage NSCLC

2018-002932-26Phase 2Completed

Sponsor
AstraZeneca
Start
Feb 2019
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Vaccines & Immunotherapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of durvalumab, oleclumab, monalizumab and danvatirsen in non-small cell lung cancer (NSCLC) (4 arms), sponsored by AstraZeneca. Primary endpoint: Clinical activity. Started Feb 2019; status: completed.

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Drugs

durvalumaboleclumabmonalizumabdanvatirsen
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Conditions

non-small cell lung cancer (NSCLC)

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