Effectiveness of repeated botulinum toxin A infiltrations on gait and quality of life in adults with spastic paraparesis due to multiple sclerosis

Phase 3, open-label, single-arm trial of botulinum toxin type A in multiple sclerosis (MS), sponsored by Aránzazu Vázquez Doce. Primary endpoints: Change in 6-minute walk test (6MWT) distance at 4 weeks after each infiltration and Maintenance of gait improvement over 12 months. Started Sep 2018; status: active.