Trial intelligence / Profile preview

M7824 with concurrent chemoradiation versus placebo with concurrent chemoradiation followed by durvalumab in unresectable stage III non-small cell lung cancer

2018-003265-34Phase 2Completed

Sponsor
Merck KGaA
Start
Apr 2019
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing cCRT plus bintrafusp alfa followed by bintrafusp alfa with cCRT plus placebo followed by durvalumab (2 arms). Primary endpoint: Progression-free survival. Started Apr 2019; status: completed.

02

Drugs

bintrafusp alfadurvalumab
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Conditions

non-small cell lung cancer (NSCLC)

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