Trial intelligence / Profile preview

Ponatinib versus imatinib-based frontline therapy in older adults with Philadelphia chromosome-positive acute lymphoblastic leukemia

2018-003350-25Phase 2Unknown

Sponsor
Cardiff University
Start
Jul 2019
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial in acute lymphoblastic leukemia (ALL) comparing Ponatinib plus chemotherapy, Ponatinib plus blinatumomab and Imatinib plus chemotherapy (3 arms). Status: unknown.

02

Drugs

ponatinibblinatumomabimatinib
03

Conditions

acute lymphoblastic leukemia (ALL)

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