Trial intelligence / Profile preview

Phase 2 Randomized Study of Cemiplimab With or Without RP1 in Cutaneous Squamous Cell Carcinoma

2018-003964-30Phase 2Active

Sponsor
Replimune Group, Inc.
Start
Nov 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Oncolytic Viruses → Oncolytic Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial in cutaneous squamous cell carcinoma (cSCC) comparing Cemiplimab monotherapy with Cemiplimab + RP1 combination (2 arms). Primary endpoint: Objective response rate by central review (overall population). Started Nov 2019; status: active.

02

Drugs

cemiplimabvusolimogene oderparepvec
03

Conditions

cutaneous squamous cell carcinoma (cSCC)

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