Trial intelligence / Profile preview

Biomarker-directed phase 2 platform study after progression on first-line osimertinib in advanced non-small cell lung cancer

2018-003974-29Phase 2Active

Sponsor
AstraZeneca
Start
May 2019
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of osimertinib, savolitinib, necitumumab, pemetrexed, carboplatin and 8 more in non-small cell lung cancer (NSCLC) (11 arms), sponsored by AstraZeneca. Primary endpoint: Objective response rate. Started May 2019; status: active.

02

Drugs

osimertinibsavolitinibnecitumumabpemetrexedcarboplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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