Trial intelligence / Profile preview

REEF-1

2019-000622-22Phase 2Unknown

Sponsor
Janssen Pharmaceutical
Start
Jun 2019
Modality
Small Molecules, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of tomligisiran, bersacapavir, entecavir, tenofovir disoproxil fumarate and tenofovir alafenamide in Chronic Hepatitis B (CHB) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Proportion of participants meeting NA treatment completion criteria at Week 48. Status: unknown.

02

Drugs

tomligisiranbersacapavirentecavirtenofovir disoproxil fumaratetenofovir alafenamide
03

Conditions

Chronic Hepatitis B (CHB)

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