Trial intelligence / Profile preview

Phase II study of avelumab + cetuximab + modified FOLFOXIRI as initial therapy for RAS wild-type unresectable metastatic colorectal cancer

2019-001501-24Phase 2Completed

Sponsor
G.O.N.O. - Gruppo Oncologico del Nord Ovest
Start
Jun 2021
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of avelumab, cetuximab, fluorouracil, oxaliplatin, irinotecan and 1 more in metastatic colorectal adenocarcinoma (mCRC), sponsored by G.O.N.O. - Gruppo Oncologico del Nord Ovest. Primary endpoint: Progression-free survival. Started Jun 2021; status: completed.

02

Drugs

avelumabcetuximabfluorouraciloxaliplatinirinotecan
03

Conditions

metastatic colorectal adenocarcinoma (mCRC)

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