Trial intelligence / Profile preview

Brigatinib versus other second-generation ALK TKIs in ALK-positive non-small cell lung cancer

2019-001828-36Phase 2Active

Sponsor
Institut für Klinische Krebsforschung
Start
Sep 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of brigatinib, alectinib and ceritinib in non-small cell lung cancer (NSCLC) and ALK-positive non-small cell lung cancer (2 arms), sponsored by Institut für Klinische Krebsforschung. Primary endpoint: Progression-free survival in first-line treatment. Started Sep 2019; status: active.

02

Drugs

brigatinibalectinibceritinib
03

Conditions

non-small cell lung cancer (NSCLC)ALK-positive non-small cell lung cancer

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