Trial intelligence / Profile preview

HOLIPANC: Neoadjuvant NAPOX Chemotherapy Followed by Curative Resection in Hepatic Oligometastatic Pancreatic Adenocarcinoma

2019-002734-37Phase 2Active

Sponsor
University of Cologne
Start
Oct 2020
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of nanoliposomal irinotecan, oxaliplatin, fluorouracil and folinic acid in pancreatic adenocarcinoma (PDAC) and pancreatic cancer (PC), sponsored by University of Cologne. Primary endpoint: Overall survival after R0/R1 resection (OS-res). Started Oct 2020; status: active.

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Drugs

nanoliposomal irinotecanoxaliplatinfluorouracilfolinic acid
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Conditions

pancreatic adenocarcinoma (PDAC)pancreatic cancer (PC)

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