Trial intelligence / Profile preview

Open-label extension study of WVE-120101 in early manifest Huntington's disease

2019-003637-42Phase 2Terminated

Sponsor
Wave Life Sciences
Start
Feb 2020
Modality
Vaccine mRNA → mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of rovanersen in Huntington disease (HD), sponsored by Wave Life Sciences. Primary endpoint: Safety and tolerability. Started Feb 2020; status: terminated.

02

Drugs

rovanersen
03

Conditions

Huntington disease (HD)

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