Trial intelligence / Profile preview

Randomized phase II trial of SBRT plus pembrolizumab with or without intratumoral avelumab + ipilimumab + myeloid dendritic cells in NSCLC

2019-003668-32Phase 2Completed

Sponsor
UZ Brussel
Start
Nov 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of pembrolizumab, avelumab and ipilimumab in non-small cell lung cancer (NSCLC) and Nonhematologic neoplasms (2 arms), sponsored by UZ Brussel. Primary endpoints: 1-year progression-free survival rate and Adverse events. Started Nov 2019; status: completed.

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Drugs

pembrolizumabavelumabipilimumab
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Conditions

non-small cell lung cancer (NSCLC)Nonhematologic neoplasms

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