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Association between methotrexate polyglutamate levels, biologic drug concentrations, and clinical response in rheumatoid arthritis

2019-003700-12Phase 4Completed

Sponsor: CHU Saint-Etienne
Start: Jun 2020
Modality: Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries: 1

Overview

Phase 4, open-label, single-arm trial of methotrexate in rheumatoid arthritis (RA), sponsored by CHU Saint-Etienne. Primary endpoint: PG-MTX concentrations. Started Jun 2020; status: completed.

Drugs

methotrexate

Conditions

rheumatoid arthritis (RA)

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