Trial intelligence / Profile preview

DUO-E trial of durvalumab with chemotherapy followed by maintenance durvalumab with or without olaparib in advanced or recurrent endometrial cancer

2019-004112-60Phase 3Active

Sponsor
AstraZeneca
Start
May 2020
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of durvalumab, olaparib, carboplatin and paclitaxel in endometrial cancer (EC) (3 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival. Started May 2020; status: active.

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Drugs

durvalumabolaparibcarboplatinpaclitaxel
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Conditions

endometrial cancer (EC)

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