Trial intelligence / Profile preview

FOLFOX plus nivolumab and ipilimumab with intrahepatic oxaliplatin for non-resectable colorectal liver metastases

2019-004397-26Phase 2Terminated

Sponsor
Herlev & Gentofte Hospital
Start
Dec 2019
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of oxaliplatin, fluorouracil, folinic acid, nivolumab and ipilimumab in colorectal cancer (CRC), sponsored by Herlev & Gentofte Hospital. Primary endpoint: Disease-free survival at 3 years without liver surgery/RFA. Started Dec 2019; status: terminated.

02

Drugs

oxaliplatinfluorouracilfolinic acidnivolumabipilimumab
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Conditions

colorectal cancer (CRC)

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