Trial intelligence / Profile preview

Switch from dolutegravir-based therapy to darunavir/cobicistat-based therapy for weight gain in adults with HIV

2019-004620-38Phase 4Terminated

Sponsor
Fight AIDS and Infectious Diseases Foundation
Start
Feb 2020
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in human immunodeficiency virus infection (HIV) comparing Triumeq continuation, Switch to Rezolsta + Kivexa and Switch to Symtuza (3 arms). Primary endpoint: Percentage of individuals with significant reduction in weight at week 48. Started Feb 2020; status: terminated.

02

Drugs

abacavirdarunavir + cobicistatabacavir + lamivudinetenofovir alafenamide
03

Conditions

human immunodeficiency virus infection (HIV)

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