Trial intelligence / Profile preview

ctDNA-guided escalation of first-line osimertinib with platinum-pemetrexed in EGFR-mutant advanced NSCLC

2019-004757-88Phase 2Active

Sponsor
Goethe University Frankfurt
Start
May 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of osimertinib, pemetrexed, carboplatin and cisplatin in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Goethe University Frankfurt. Primary endpoint: Progression-free survival (PFS1). Started May 2021; status: active.

02

Drugs

osimertinibpemetrexedcarboplatincisplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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