Trial intelligence / Profile preview

SAR408701 plus pembrolizumab versus pembrolizumab alone in CEACAM5- and PD-L1-positive advanced non-squamous non-small cell lung cancer

2020-000035-50Phase 2Active

Sponsor
Sanofi
Start
Apr 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial in Non-small cell lung cancer (NS-NSCLC) comparing SAR408701 plus pembrolizumab with Pembrolizumab alone (2 arms). Primary endpoint: Number of participants with study drug-related dose-limiting toxicities. Started Apr 2020; status: active.

02

Drugs

tusamitamab ravtansinepembrolizumab
03

Conditions

Non-small cell lung cancer (NS-NSCLC)

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