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GDC-9545 plus palbociclib versus letrozole plus palbociclib in first-line ER-positive, HER2-negative advanced breast cancer
2020-000119-66Phase 3Active
- Sponsor
- Roche
- Start
- Sep 2020
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, double-blind trial in breast cancer comparing GDC-9545 + palbociclib with letrozole + palbociclib (2 arms). Primary endpoint: Progression-free survival. Started Sep 2020; status: active.
02
Drugs
giredestrantpalbociclibletrozole
03
Conditions
breast cancer
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