Trial intelligence / Profile preview

Discontinuation and re-treatment with pexidartinib in tenosynovial giant cell tumor

2020-000192-20Phase 4Completed

Sponsor
Daiichi Sankyo Co., Ltd.
Start
Jun 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label trial of pexidartinib in tenosynovial giant cell tumor (TGCT) and giant cell tumor of tendon sheath (GCTTS) (2 arms), sponsored by Daiichi Sankyo Co., Ltd. Primary endpoints: Proportion of subjects who remain treatment-free at Month 12 and Proportion of subjects who remain treatment-free at Month 24. Started Jun 2020; status: completed.

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Drugs

pexidartinib
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Conditions

tenosynovial giant cell tumor (TGCT)giant cell tumor of tendon sheath (GCTTS)

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