Trial intelligence / Profile preview

Amivantamab plus carboplatin-pemetrexed versus carboplatin-pemetrexed in EGFR exon 20 insertion-mutated advanced or metastatic non-small cell lung cancer

2020-000633-40Phase 3Active

Sponsor
Janssen Pharmaceutical
Start
Sep 2020
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Amivantamab + carboplatin + pemetrexed with Carboplatin + pemetrexed (2 arms). Primary endpoint: Progression-free survival. Started Sep 2020; status: active.

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Drugs

amivantamabcarboplatinpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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