Trial intelligence / Profile preview

Amivantamab + lazertinib versus osimertinib versus lazertinib in first-line EGFR-mutated advanced or metastatic NSCLC

2020-000743-31Phase 3Active

Sponsor
Janssen Pharmaceutical
Start
Jun 2020
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised trial of amivantamab, lazertinib and osimertinib in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Progression-free survival. Started Jun 2020; status: active.

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Drugs

amivantamablazertinibosimertinib
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Conditions

non-small cell lung cancer (NSCLC)

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