Trial intelligence / Profile preview

Defibrotide to reduce progression of acute respiratory failure in severe COVID-19 pneumonia

2020-001513-20Phase 2Completed

Sponsor
IRCCS Ospedale San Raffaele
Start
Jun 2020
Modality
Vaccine mRNA → mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
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Overview

Phase 2 trial of defibrotide in coronavirus pneumonia and coronavirus disease 2019 (COVID-19) (2 arms), sponsored by IRCCS Ospedale San Raffaele. Primary endpoint: Respiratory-failure rate (RFR). Started Jun 2020; status: completed.

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Drugs

defibrotide
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Conditions

coronavirus pneumoniacoronavirus disease 2019 (COVID-19)

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