Trial intelligence / Profile preview

Phase 3 first-line advanced clear cell renal cell carcinoma study of pembrolizumab + belzutifan + lenvatinib or quavonlimab/pembrolizumab + lenvatinib versus pembrolizumab + lenvatinib

2020-002216-52Phase 3Active

Sponsor
Merck & Co.
Start
Feb 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab, belzutifan, lenvatinib and quavonlimab + pembrolizumab in clear cell renal cell carcinoma (ccRCC) (3 arms), sponsored by Merck & Co. Primary endpoint: Progression-Free Survival. Started Feb 2021; status: active.

02

Drugs

pembrolizumabbelzutifanlenvatinibquavonlimab + pembrolizumab
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Conditions

clear cell renal cell carcinoma (ccRCC)

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