Trial intelligence / Profile preview

T-cell Therapy Plus Nivolumab, Relatlimab, and Ipilimumab in Advanced Ovarian and Related Cancers

2020-002738-34Phase 2Terminated

Sponsor
National Center for Cancer Immune Therapy
Start
Jul 2020
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of autologous tumor-infiltrating lymphocytes, nivolumab, relatlimab, ipilimumab, cyclophosphamide and 1 more in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC), sponsored by National Center for Cancer Immune Therapy. Primary endpoints: Toxicity and Feasibility. Started Jul 2020; status: terminated.

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Drugs

autologous tumor-infiltrating lymphocytesnivolumabrelatlimabipilimumabcyclophosphamide
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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