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Phase 3 trial of standard DA + gemtuzumab ozogamicin vs CPX-351 + gemtuzumab ozogamicin in pediatric de novo AML

2020-002762-13Phase 3

Sponsor
Children's Oncology Group
Start
Oct 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial of gemtuzumab ozogamicin, daunorubicin + cytarabine liposome, daunorubicin, cytarabine and gilteritinib in acute myeloid leukemia (AML) (2 arms), sponsored by Children's Oncology Group. Primary endpoint: Event-free survival (EFS).

02

Drugs

gemtuzumab ozogamicindaunorubicin + cytarabine liposomedaunorubicincytarabinegilteritinib
03

Conditions

acute myeloid leukemia (AML)

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