Trial intelligence / Profile preview

Phase II intratumoral L19IL2 + L19TNF in non-melanoma skin cancer

2020-003299-42Phase 2Active

Sponsor
Philogen
Start
Nov 2020
Modality
Immunomodulatory ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Cytokines & Interferons → Recombinant Proteins and Enzymes, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of darleukin and onfekafusp alfa in basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC) and non-melanoma skin cancer (NMSC), sponsored by Philogen. Primary endpoint: Confirmed Best Overall Response Rate for basal cell carcinoma. Started Nov 2020; status: active.

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Drugs

darleukinonfekafusp alfa
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Conditions

basal cell carcinoma (BCC)cutaneous squamous cell carcinoma (cSCC)non-melanoma skin cancer (NMSC)

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