Trial intelligence / Profile preview

Three-period randomized withdrawal study of MAS825 in NLRC4-GOF

2020-003596-17Phase 2Active

Sponsor
Novartis
Start
Jan 2021
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial in NLRC4-associated autoinflammatory disease (NLRC4-AID) and necrotizing enterocolitis (NEC) comparing MAS825 with Placebo (2 arms). Primary endpoint: Occurrence of disease flare during randomized withdrawal period. Started Jan 2021; status: active.

02

Drugs

MAS825
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Conditions

NLRC4-associated autoinflammatory disease (NLRC4-AID)necrotizing enterocolitis (NEC)

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