Trial intelligence / Profile preview

GEOMETRY-E: capmatinib + osimertinib versus platinum-pemetrexed chemotherapy in MET-amplified EGFR-mutated NSCLC after EGFR-TKI failure

2020-003677-21Phase 3Terminated

Sponsor
Novartis
Start
Apr 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of capmatinib, osimertinib, pemetrexed, cisplatin and carboplatin in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Novartis. Started Apr 2021; status: terminated.

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Drugs

capmatinibosimertinibpemetrexedcisplatincarboplatin
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Conditions

non-small cell lung cancer (NSCLC)

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