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Hydrocortisone + fludrocortisone for critical illness-related corticosteroid insufficiency
2020-003942-35Phase 3Active
- Sponsor
- Assistance publique - Hôpitaux de Paris
- Start
- Jan 2021
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised trial in Relative adrenal insufficiency (CIRCI) comparing Hydrocortisone + fludrocortisone with Placebo (2 arms). Primary endpoint: Ventilator- and vasopressor-free days through day 30. Started Jan 2021; status: active.
02
Drugs
hydrocortisonefludrocortisone
03
Conditions
Relative adrenal insufficiency (CIRCI)
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