Trial intelligence / Profile preview

Phase II open-label single-arm study of AZD2811 plus durvalumab in first-line extensive-stage small-cell lung cancer

2020-004091-18Phase 2Completed

Sponsor
AstraZeneca
Start
May 2021
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 2, open-label, single-arm trial of defosbarasertib and durvalumab in small cell lung cancer (SCLC), sponsored by AstraZeneca. Primary endpoint: Maintenance participants alive and progression free at 12 months (APF12). Started May 2021; status: completed.

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Drugs

defosbarasertibdurvalumab
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Conditions

small cell lung cancer (SCLC)

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