Trial intelligence / Profile preview

ALBATROS phase II lorlatinib after first-line ROS1 TKI failure in advanced ROS1-positive NSCLC

2020-004466-19Phase 2Active

Sponsor
IFCT
Start
Oct 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of lorlatinib in non-small cell lung cancer (NSCLC), sponsored by IFCT. Primary endpoint: Objective response rate at 8 weeks. Started Oct 2020; status: active.

02

Drugs

lorlatinib
03

Conditions

non-small cell lung cancer (NSCLC)

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