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Phase II trial of PD1-TIM3 bispecific antibody RO7121661 and PD1-LAG3 bispecific antibody RO7247669 versus nivolumab in advanced or metastatic esophageal squamous cell carcinoma

2020-004606-60Phase 2Completed

Sponsor
Roche
Start
Feb 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial in Esophageal Squamous Cell Carcinoma (ESCC) comparing RO7121661 arm, RO7247669 arm and Nivolumab arm (3 arms). Primary endpoint: Overall survival. Started Feb 2021; status: completed.

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Drugs

lomvastomigtobemstomignivolumab
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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