Trial intelligence / Profile preview

Crovalimab as adjunct treatment to prevent vaso-occlusive episodes in sickle cell disease

2020-004839-25Phase 2Active

Sponsor
Roche
Start
Jul 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial in sickle cell disease (SCD) and vaso-occlusive crisis (VOC) comparing Crovalimab with Placebo (2 arms). Primary endpoint: Annualized rate of medical facility vaso-occlusive episodes (AVR). Started Jul 2021; status: active.

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Drugs

crovalimab
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Conditions

sickle cell disease (SCD)vaso-occlusive crisis (VOC)

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