Trial intelligence / Profile preview

Pozelimab and cemdisiran combination after pozelimab monotherapy in PNH

2020-005005-17Phase 2Completed

Sponsor
Regeneron Pharmaceuticals
Start
Mar 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of pozelimab and cemdisiran in paroxysmal nocturnal hemoglobinuria (PNH) (2 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Incidence and severity of treatment-emergent adverse events. Started Mar 2021; status: completed.

02

Drugs

pozelimabcemdisiran
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)

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