Trial intelligence / Profile preview

MK-1308A-008 in MSI-H/dMMR stage IV colorectal cancer

2020-005114-18Phase 2Active

Sponsor
Merck & Co.
Start
Mar 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of quavonlimab, pembrolizumab, favezelimab, vibostolimab and mk-4830 in colorectal cancer (CRC) (5 cohorts), sponsored by Merck & Co. Primary endpoint: Objective Response Rate. Started Mar 2021; status: active.

02

Drugs

quavonlimabpembrolizumabfavezelimabvibostolimabmk-4830
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Conditions

colorectal cancer (CRC)

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