Trial intelligence / Profile preview

Randomized Double-Blind Placebo-Controlled Phase 2/3 Study of BLU-263 (elenestinib) in Indolent Systemic Mastocytosis

2020-005173-28Phase 2Active

Sponsor
Blueprint Medicines
Start
Jun 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in indolent systemic mastocytosis (ISM) and monoclonal mast cell activation syndrome (MMAS) comparing BLU-263 with Placebo (2 arms). Primary endpoint: Part 1 primary endpoint. Started Jun 2021; status: active.

02

Drugs

elenestinib
03

Conditions

indolent systemic mastocytosis (ISM)monoclonal mast cell activation syndrome (MMAS)

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