Trial intelligence / Profile preview

LIBRETTO-432 adjuvant selpercatinib vs placebo in stage IB–IIIA RET fusion-positive NSCLC

2020-005191-35Phase 3Active

Sponsor
Eli Lilly and Company
Start
May 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Selpercatinib with Placebo (2 arms). Primary endpoints: Event-free survival in primary analysis population and Event-free survival in overall population. Started May 2021; status: active.

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Drugs

selpercatinib
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Conditions

non-small cell lung cancer (NSCLC)

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