Trial intelligence / Profile preview

Dato-DXd versus investigator's choice chemotherapy in previously treated HR-positive, HER2-negative metastatic breast cancer

2020-005620-12Phase 3Active

Sponsor
AstraZeneca
Start
Oct 2021
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of datopotamab deruxtecan in breast cancer and hormone receptor-positive/HER2-negative breast cancer (2 arms), sponsored by AstraZeneca. Primary endpoints: Progression-free survival and Objective response rate. Started Oct 2021; status: active.

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Drugs

datopotamab deruxtecan
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Conditions

breast cancerhormone receptor-positive/HER2-negative breast cancer

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