Trial intelligence / Profile preview

AMA-VACC study of SARS-CoV-2 vaccine response in secondary progressive multiple sclerosis patients treated with siponimod

2020-005752-38Phase 4Completed

Sponsor
Novartis
Start
Jan 2021
Modality
Small Molecules, Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 4, open-label trial of siponimod and RH109 in secondary-progressive multiple sclerosis (SPMS) and coronavirus disease 2019 (COVID-19) (4 arms), sponsored by Novartis. Primary endpoint: Primary: Seroconversion after second vaccine dose. Started Jan 2021; status: completed.

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Drugs

siponimodRH109
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Conditions

secondary-progressive multiple sclerosis (SPMS)coronavirus disease 2019 (COVID-19)

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