Trial intelligence / Profile preview

Neoadjuvant encorafenib + binimetinib + cetuximab in BRAF V600E pMMR localized colorectal cancer

2020-005771-12Phase 2Terminated

Sponsor
AIO-Studien
Start
Feb 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of cetuximab, encorafenib and binimetinib in colorectal cancer (CRC), colon cancer and rectal cancer, sponsored by AIO-Studien. Primary endpoint: Tumor regression grade (TRG). Started Feb 2022; status: terminated.

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Drugs

cetuximabencorafenibbinimetinib
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Conditions

colorectal cancer (CRC)colon cancerrectal cancer

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