Trial intelligence / Profile preview

Trametinib versus vinblastine in newly diagnosed BRAF wild-type non-NF1 pediatric and AYA low-grade glioma

2020-005786-14Phase 2Active

Sponsor
Strasbourg University Hospital
Start
Jul 2021
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in glioma, Glioneuronal Neoplasm and pleomorphic xanthoastrocytoma (PXA) comparing Trametinib arm with Vinblastine arm (2 arms). Primary endpoint: 3-year progression-free survival. Started Jul 2021; status: active.

02

Drugs

trametinibvinblastine
03

Conditions

gliomaGlioneuronal Neoplasmpleomorphic xanthoastrocytoma (PXA)

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