Trial intelligence / Profile preview

Ponatinib plus blinatumomab versus chemotherapy plus imatinib for newly diagnosed adult Philadelphia chromosome-positive acute lymphoblastic leukemia

2020-006048-15Phase 3Active

Sponsor
GIMEMA
Start
Jun 2021
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial of ponatinib, blinatumomab and imatinib in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by GIMEMA. Primary endpoint: Event-free survival. Started Jun 2021; status: active.

02

Drugs

ponatinibblinatumomabimatinib
03

Conditions

acute lymphoblastic leukemia (ALL)

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