Trial intelligence / Profile preview

Reduced-dose-intensity versus standard checkpoint inhibitor immunotherapy after 6 months of response in metastatic cancer

2021-000615-23Phase 3Active

Sponsor
Unicancer
Start
Jun 2021
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, open-label trial of pembrolizumab, durvalumab, atezolizumab, avelumab, nivolumab and 3 more in non-small cell lung cancer (NSCLC), metastatic renal cell carcinoma (mRCC), head and neck cancer (HNC) and 5 more (2 arms), sponsored by Unicancer. Primary endpoint: Progression-free survival. Started Jun 2021; status: active.

02

Drugs

pembrolizumabdurvalumabatezolizumabavelumabnivolumab
03

Conditions

non-small cell lung cancer (NSCLC)metastatic renal cell carcinoma (mRCC)head and neck cancer (HNC)bladder cancertriple-negative breast cancer (TNBC)

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