Trial intelligence / Profile preview

AGORA-1 / ALFA 2100: Gemtuzumab ozogamicin + gilteritinib in FLT3-ITD relapsed/refractory AML

2021-001813-35Phase 2Active

Sponsor
Centre Antoine Lacassagne
Start
Jan 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, single-arm trial of gilteritinib and gemtuzumab ozogamicin in acute myeloid leukemia (AML), sponsored by Centre Antoine Lacassagne. Primary endpoint: Safety of adding gilteritinib to AGORA treatment platform. Started Jan 2022; status: active.

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Drugs

gilteritinibgemtuzumab ozogamicin
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Conditions

acute myeloid leukemia (AML)

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