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Amivantamab and lazertinib plus platinum-based chemotherapy versus platinum-based chemotherapy after osimertinib failure in EGFR-mutated advanced non-small cell lung cancer
2021-001825-33Phase 3Active
- Sponsor
- Janssen Pharmaceutical
- Start
- Aug 2021
- Modality
- DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of amivantamab, lazertinib, carboplatin and pemetrexed in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Progression-free survival. Started Aug 2021; status: active.
02
Drugs
amivantamablazertinibcarboplatinpemetrexed
03
Conditions
non-small cell lung cancer (NSCLC)
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