Trial intelligence / Profile preview

GEN1046 monotherapy and combination therapy in relapsed/refractory metastatic non-small cell lung cancer after prior immune checkpoint inhibitor treatment

2021-001928-17Phase 2Active

Sponsor
Genmab
Start
Jul 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing GEN1046 monotherapy with GEN1046 + Keytruda (2 arms). Primary endpoint: Objective response rate. Started Jul 2021; status: active.

02

Drugs

acasunlimabpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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