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Encorafenib + binimetinib + pembrolizumab versus nivolumab + ipilimumab in BRAF V600E/K melanoma after anti-PD-1 progression

2021-003640-24Phase 2Active

Sponsor
Pfizer
Start
Nov 2022
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of encorafenib, binimetinib, pembrolizumab, nivolumab and ipilimumab in melanoma (2 arms), sponsored by Pfizer. Primary endpoint: ORR. Started Nov 2022; status: active.

02

Drugs

encorafenibbinimetinibpembrolizumabnivolumabipilimumab
03

Conditions

melanoma

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