Trial intelligence / Profile preview

Sapablursen in phlebotomy-dependent polycythemia vera

2021-003704-40Phase 2Terminated

Sponsor
Ionis Pharmaceuticals
Start
Dec 2022
Modality
Gene Therapies, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of sapablursen in polycythemia vera (PV), sponsored by Ionis Pharmaceuticals. Primary endpoint: Reduction in the frequency of phlebotomy comparing baseline with the last 20 weeks of the 37-week treatment period. Started Dec 2022; status: terminated.

02

Drugs

sapablursen
03

Conditions

polycythemia vera (PV)

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