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Relatlimab + nivolumab versus regorafenib or trifluridine + tipiracil in later-line metastatic colorectal cancer

2021-004285-35Phase 3Active

Sponsor
Bristol Myers Squibb
Start
Mar 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in metastatic colorectal adenocarcinoma (mCRC) comparing Relatlimab + nivolumab fixed-dose combination, Regorafenib and Trifluridine + tipiracil (3 arms). Primary endpoint: Overall Survival. Started Mar 2022; status: active.

02

Drugs

relatlimabnivolumabregorafenibtrifluridinetipiracil
03

Conditions

metastatic colorectal adenocarcinoma (mCRC)

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